The Journal of Preventive Medicine
نویسندگان
چکیده
Streptococcus pneumoniaemajor cause of infection in children causes serious therapeutic difficulties, because of the developed multiresistance. Extended-spectrum cephalosporins, used in empirical therapy are a therapeutic option. Recent emergence of Ceftriaxone (CRO) and Cefotaxime (CTX) resistant strains with regional differences in frequency requires their detection by quantitative determinations. The results of the first study on children from Iasi concerning CRO resistance of S. pneumoniae, evaluated according to NCCLS 2002 criteria, showed the presence of this phenotype in ear and lower respiratory tract infections. Authors recommend quantitative testing for CRO of high level P resistant strains, isolated from these infections, when CRO is a therapeutic option and surveillance of occurrence of this resistance phenotype in strains isolated from non respiratory infections.
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